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Volume 15 No. 11
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Accepted Papers

Scientific Investigations

Association Between Late Bedtime and Diabetes Mellitus: A Large Community-Based Study

Bin Yan, MD1,2,*; Yajuan Fan, MD2,*; Binbin Zhao, MD2; Xiaoyan He, MD2; Jian Yang, MD1; Ce Chen, MD2; Xiancang Ma, MD, PhD2,3
1Department of Clinical Research Centre, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; 2Department of Psychiatry, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; 3Brain Science Centre for Translational Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

Study Objectives:

The aim of this study was to investigate the association of bedtime with the prevalence of diabetes mellitus (DM) based on a large community-based population.


In total, 5,420 participants (2,574 males and 2,846 females; aged 63.5 ± 11.0 years) from the Sleep Heart Health Study database were selected in this study. Sleep habit was recorded based on a questionnaire administered to patients upon recruitment. Bedtime was categorized as 11:00 pm and before, 11:00 pm to 12:00 am, and 12:00 am and later in the current study. Multivariate logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) to determine the relationship between bedtime and the prevalence of DM.


The distribution of weekday bedtime at 11:00 pm and before, 11:00 pm to 12:00 am, 12:00 am and later was observed in 3,316 participants (61.2%), 991 participants (18.3%), and 1,113 participants (20.5%), respectively. Meanwhile, individuals with weekday bedtime of 12:00 am and later had a higher prevalence of DM than those with bedtime at 11:00 pm to 12:00 am, and 11:00 pm and before (10.6% versus 5.7% versus 6.6%, respectively; P < .001). In the adjusted multivariate logistic regression model, bedtime at 12:00 am and later on a weekday was significantly associated DM prevalence (OR 1.446, 95% CI 1.107–1.888, P = .007). No significant association was found between weekend bedtime and DM.


Late bedtime at 12:00 am and later on a weekday may be a risk factor for the prevalence of DM. Stable sleep timing leads to lower risk of DM deserves future exploration.


Yan B, Fan Y, Zhao B, He X, Yang J, Chen C, Ma X. Association between late bedtime and diabetes mellitus: A large community-based study. J Clin Sleep Med. 2019;15(11):1621–1627.

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