Issue Navigator

Volume 15 No. 10
Earn CME
Accepted Papers

Scientific Investigations

Evolution and Predictive Factors of Improvement of Obstructive Sleep Apnea in an Obese Population After Bariatric Surgery

Fanny Magne, MD1; Emmanuel Gomez, MD1; Olivier Marchal, PhD2; Pascale Malvestio1; Nicolas Reibel, MD3; Laurent Brunaud, PhD3; Olivier Ziegler, PhD1; Didier Quilliot, PhD4; François Chabot, PhD1,5; Ari Chaouat, PhD1,5
1CHU Nancy, Pôles des Spécialités Médicales/Département de Pneumologie, Vandoeuvre-lès-Nancy, France; 2Institut Camille Jordan UMR 5208, Université Jean Monnet, Lyon, France; 3CHU Nancy, Pôle Digestif/Service de Chirurgie Générale et d’Urgences, Nancy, France; 4CHU Nancy, Pôles des Spécialités Médicales/Département de Diabétologie, Maladies Métaboliques et Nutrition, Vandoeuvre-lès-Nancy, France; 5Inserm, U1116, Université de Lorraine, Nancy, France

Study Objectives:

Our objectives were to determine in an obese population (body mass index > 35 kg/m2) the number of patients, after gastric bypass (GBP), who no longer met French Ministry of Health criteria for utilizing positive airway pressure (PAP), and the predictive factors of obstructive sleep apnea (OSA) improvement.


Between June 2012 and August 2014 we diagnosed OSA in 129 incident patients requiring PAP therapy before GBP. A postoperative sleep recording was undertaken for 44 of these patients after a weight loss of at least 10%.


Most of the patients showed severe OSA with a mean [standard deviation] apnea-hypopnea index (AHI) of 52.8 [23.8] events/h. The body mass index was 46.1 [5.1] kg/m2. All the patients were treated via PAP and most of them via auto-titrating PAP with a range of 4–16 cmH2O. Following the GBP, in 31 patients (70.5%) OSA was improved, allowing PAP to be stopped (AHI < 15 events/h). The Epworth Sleepiness Scale score, the modified Medical Research Council dyspnea scale, the loudness of snoring, and sleep structure were improved. AHI was decreased by a mean of 40.9 [22.4] events/h (P < .001). In a multivariate logistic regression model, age (P = .018) and sleep oxygen desaturation index (P = .049) appeared to predict improvement of OSA.


After GBP, 70.5% of the patients no longer met French Ministry of Health criteria for utilizing PAP, allowing discontinuation of this treatment. At diagnosis, a younger age and a less severe sleep oxygen desaturation were predictive factors of this improvement.


Magne F, Gomez E, Marchal O, Malvestio P, Reibel N, Brunaud L, Ziegler O, Quilliot D, Chabot F, Chaouat A. Evolution and predictive factors of improvement of obstructive sleep apnea in an obese population after bariatric surgery. J Clin Sleep Med. 2019;15(10):1509–1516.

Please login to continue reading the full article

Subscribers to JCSM get full access to current and past issues of the JCSM.

Login to JCSM

Not a subscriber?

Join the American Academy of Sleep Medicine and receive a subscription to JCSM with your membership

Subscribe to JCSM:  $125/volume year for individuals or $225/volume year for institutions to access all current articles and archives published in JCSM.

Download this article*:   $20 to access a PDF version of a specific article from the current issue of JCSM.

*Purchase of an article provides permission to access and print the article for personal scholarly, research and educational use. Please note: access to the article is from the computer on which the article is purchased ONLY. Purchase of the article does not permit distribution, electronic or otherwise, of the article without the written permission of the AASM. Further, purchase does not permit the posting of article text on an online forum or website.