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Volume 15 No. 09
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Accepted Papers

Case Reports

Unexpected Finding of Idiopathic REM Sleep Behavior Disorder in a Young Healthy Male With Snoring: A Case Report

Matthew S. Brock, MD1; Sean Shirley, MD1; Luis Rohena, MD2; Brian A. Moore, MA3,4; Vincent Mysliwiec, MD1
1Department of Sleep Medicine, Wilford Hall Ambulatory Surgical Center, San Antonio, Texas; 2Department of Pediatrics, Division of Medical Genetics, San Antonio Military Medical Center, San Antonio, Texas; 3The University of Texas Health Science Center at San Antonio, San Antonio, Texas; 4The University of Texas at San Antonio, San Antonio, Texas

Idiopathic rapid eye movement sleep behavior disorder is characterized by vocalizations and complex motor behaviors during sleep. We report a case of a 44-year-old male with a 20-year history of dream enactment behavior that was incidentally captured on a polysomnogram during an evaluation for obstructive sleep apnea. Genetic testing found the patient had a homozygous deletion for one of the five tandem repeats in exon 18 of the PER3 gene. This case highlights a potential genetic basis for idiopathic rapid eye movement sleep behavior disorder.


Brock MS, Shirley S, Rohena L, Moore BA, Mysliwiec V. Unexpected finding of idiopathic REM sleep behavior disorder in a young healthy male with snoring: a case report. J Clin Sleep Med. 2019;15(9):1369–1371.

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