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Volume 15 No. 07
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Accepted Papers

Case Reports

Steroids: A Wake-Up Call in TBI Induced Hypersomnolence

Margarita Oks, MD1; Sanjeev V. Kothare, MD2
1Lenox Hill Hospital – Northwell Health System, Department of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York; 2Cohen Children's Medical Center, Pediatric Sleep Program, Department of Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York

Hypersomnolence is one of the more common symptoms reported after mild traumatic brain injury (TBI) and often one of the most difficult to treat. This case series presents a cohort of patients with TBI related hypersomnolence associated with a de novo autoimmune process that successfully resolved with pulse dose corticosteroid treatment. When associated with an autoimmune inflammatory process, corticosteroids may serve to stabilize the blood brain barrier leading to the successful and sustained resolution of TBI induced sleepiness.


Oks M, Kothare SV. Steroids: a wake-up call in TBI induced hypersomnolence. J Clin Sleep Med. 2019;15(7):1063–1065.

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