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Volume 14 No. 03
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Accepted Papers

Scientific Investigations

Long-Term Impact of Sleep-Disordered Breathing on Quality of Life in Children With Obesity

Sherri L. Katz, MDCM, MSc1; Joanna E. MacLean, MD, PhD2; Nicholas Barrowman, PhD3; Lynda Hoey3; Linda Horwood, MSc4; Glenda N. Bendiak, MD, MSc5; Valerie G. Kirk, MD5; Stasia Hadjiyannakis, MD1; Laurent Legault, MD4; Bethany J. Foster, MD, MSCE4; Evelyn Constantin, MDCM, MSc(Epi)4
1Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada; 2Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada; 3Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada; 4Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada; 5Alberta Children's Hospital, University of Calgary, Calgary, Alberta, Canada

Study Objectives:

(1) To determine baseline quality of life (QOL) among children with obesity and newly diagnosed moderate-severe sleep-disordered breathing (SDB) and to compare it to the reported QOL of children with obesity or SDB alone and healthy children. (2) To evaluate QOL change after 1 year.


A prospective multicenter cohort study was conducted in children (8–16 years) with obesity, prescribed positive airway pressure (PAP) therapy for moderate-severe SDB. Outcomes included parent-proxy and self-report total and subscale scores on the PedsQL questionnaire (baseline and 1-year).


Total PedsQL scores were indicative of impaired QOL in 69% of cases based on parent-report and in 62% on self-report. Parents reported significantly lower QOL in our cohort than that reported in other studies for children with obesity or SDB alone or healthy children, on total PedsQL score and on social and psychosocial subscales. PedsQL total scores for participants were significantly higher (mean difference 7.3 ± 15.3, P = .03) than those reported by parents. Parents reported significant improvements in total PedsQL (mean change 7.29 ± 13.73, P = .04) and social functioning (mean change 17.65 ± 24.69, P = .04) scores after 1 year. No significant differences were found by children's self-report or by PAP adherence.


QOL of children with obesity and SDB is lower than in children with obesity or SDB alone or healthy children. One year later, children reported no significant changes in QOL; parents reported significant improvements in total PedsQL and social functioning scores. PAP adherence did not significantly affect QOL change in this population.


A commentary on this article appears in this issue on page 307.


Katz SL, MacLean JE, Barrowman N, Hoey L, Horwood L, Bendiak GN, Kirk VG, Hadjiyannakis S, Legault L, Foster BJ, Constantin E. Long-term impact of sleep-disordered breathing on quality of life in children with obesity. J Clin Sleep Med. 2018;14(3):451–458.

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