Guilleminault C, Brooks SN. Excessive daytime sleepiness: a challenge for the practising neurologist. Brain. 2001;124(Pt 8):1482–1491. [PubMed]
Bixler EO, Vgontzas AN, Ten Have T, Tyson K, Kales A. Effects of age on sleep apnea in men: I. Prevalence and severity. Am J Respir Crit Care Med. 1998;157(1):144–148. [PubMed]
Bixler EO, Vgontzas AN, Lin HM, et al. Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med. 2001;163(3 Pt 1):608–613. [PubMed]
Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto FJ. Sleepiness in patients with moderate to severe sleep-disordered breathing. Sleep. 2005;28(4):472–477. [PubMed]
Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328(17):1230–1235. [PubMed]
Cao MT, Guilleminault C, Kushida CA. Clinical features and evaluation of obstructive sleep apnea and upper airway resistance. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine. 5th ed. Philadelphia, PA: WB Saunders; 2011:1206–1218.
Li Y, Vgontzas AN, Fernandez-Mendoza J, et al. Objective, but not subjective, sleepiness is associated with inflammation in sleep apnea. Sleep. 2017;40(2).
Dinges DF, Powell JW. Microcomputer analyses of performance on a portable, simple visual RT task during sustained operations. Behav Res Methods Instrum Comput. 1985;17(6):652–655.
Dorrian J, Rogers NL, Dinges DF. Psychomotor vigilance performance: a neurocognitive assay sensitive to sleep loss. In: Kushida C, ed. Sleep Deprivation: Clinical Issues, Pharmacology and Sleep Loss Effects. New York, NY: Marcel Dekker, Inc.; 2005:39–70.
Dinges DF, Pack F, Williams K, et al. Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per night. Sleep. 1997;20(4):267–277. [PubMed]
Batool-Anwar S, Kales SN, Patel SR, Varvarigou V, DeYoung PN, Malhotra A. Obstructive sleep apnea and psychomotor vigilance task performance. Nat Sci Sleep. 2014;6:65–71. [PubMed Central][PubMed]
Sforza E, Haba-Rubio J, De Bilbao F, Rochat T, Ibanez V. Performance vigilance task and sleepiness in patients with sleep-disordered breathing. Eur Respir J. 2004;24(2):279–285. [PubMed]
Van Dongen HP, Maislin G, Mullington JM, Dinges DF. The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. Sleep. 2003;26(2):117–126. [PubMed]
Vgontzas AN, Zoumakis E, Bixler EO, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab. 2004;89(5):2119–2126. [PubMed]
Pejovic S, Basta M, Vgontzas AN, et al. Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance. Am J Physiol Endocrinol Metab. 2013;305(7):E890–E896. [PubMed Central][PubMed]
Franzen PL, Siegle GJ, Buysse DJ. Relationships between affect, vigilance, and sleepiness following sleep deprivation. J Sleep Res. 2008;17(1):34–41. [PubMed Central][PubMed]
Bédard MA, Montplaisir J, Richer F, Malo J. Nocturnal hypoxemia as a determinant of vigilance impairment in sleep apnea syndrome. Chest. 1991;100(2):367–370. [PubMed]
Barbé, Pericás J, Muñoz A, Findley L, Antó JM, Agustí AG. Automobile accidents in patients with sleep apnea syndrome. An epidemiological and mechanistic study. Am J Respir Crit Care Med. 1998;158(1):18–22. [PubMed]
Kim H, Dinges DF, Young T. Sleep-disordered breathing and psychomotor vigilance in a community-based sample. Sleep. 2007;30(10):1309–1316. [PubMed Central][PubMed]
Dinges DF, Weaver TE. Effects of modafinil on sustained attention performance and quality of life in OSA patients with residual sleepiness while being treated with nCPAP. Sleep Med. 2003;4(5):393–402. [PubMed]
Bixler EO, Vgontzas AN, Lin HM, Calhoun SL, Vela-Bueno A, Kales A. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. J Clin Endocrinol Metab. 2005;90(8):4510–4515. [PubMed]
Vgontzas AN, Tan TL, Bixler EO, Martin LF, Shubert D, Kales A. Sleep apnea and sleep disruption in obese patients. Arch Intern Med. 1994;154(15):1705–1711. [PubMed]
Phillips BA, Collop NA, Drake C, Consens F, Vgontzas AN, Weaver TE. Sleep disorders and medical conditions in women. J Womens Health. 2008;17(7):1191–1199.
Littner MR, Kushida C, Wise M, et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep. 2005;28(1):113–121. [PubMed]
American Academy of Sleep Medicine. International Classification of Sleep Disorders. 3rd ed. Darien, IL: American Academy of Sleep Medicine; 2014.
Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–545. [PubMed]
Vgontzas AN, Papanicolaou DA, Bixler EO, et al. Circadian interleukin-6 secretion and quantity and depth of sleep. J Clin Endocrinol Metab. 1999;84(8):2603–2607. [PubMed]
Vgontzas AN, Pejovic S, Zoumakis E, et al. Daytime napping after a night of sleep loss decreases sleepiness, improves performance, and causes beneficial changes in cortisol and interleukin-6 secretion. Am J Physiol Endocrinol Metab. 2007;292(1):E253–E261. [PubMed]
Thomann J, Baumann CR, Landolt HP, Werth E. Psychomotor vigilance task demonstrates impaired vigilance in disorders with excessive daytime sleepiness. J Clin Sleep Med. 2014;10(9):1019–1024. [PubMed Central][PubMed]
van der Meere J, Börger N, van Os T. Sustained attention in major unipolar depression. Percept Mot Skills. 2007;104(3 Pt 2):1350–1354. [PubMed]
Porter RJ, Gallagher P, Thompson JM, Young AH. Neurocognitive impairment in drug-free patients with major depressive disorder. Br J Psychiatry. 2003;182:214–220. [PubMed]
Dinges DF, Kribbs NB. Performing while sleepy: effects of experimentally-induced sleepiness. In: Monk TH, ed. Sleep, Sleepiness and Performance. Oxford, England: John Wiley & Sons; 1991:97–128.
Doran SM, Van Dongen HP, Dinges DF. Sustained attention performance during sleep deprivation: evidence of state instability. Arch Ital Biol. 2001;139(3):253–267. [PubMed]
Basta M, Chrousos GP, Vela-Bueno A, Vgontzas AN. Chronic insomnia and stress system. Sleep Med Clin. 2007;2(2):279–291. [PubMed Central][PubMed]
Theorell-Haglöw J, Lindberg E, Janson C. What are the important risk factors for daytime sleepiness and fatigue in women? Sleep. 2006;29(6):751–757. [PubMed]
Bardwell WA, Ancoli-Israel S, Dimsdale JE. Comparison of the effects of depressive symptoms and apnea severity on fatigue in patients with obstructive sleep apnea: a replication study. J Affect Disord. 2007;97(1-3):181–186. [PubMed]
Sforza E, de Saint Hilaire Z, Pelissolo A, Rochat T, Ibanez V. Personality, anxiety and mood traits in patients with sleep-related breathing disorders: effect of reduced daytime alertness. Sleep Med. 2002;3(2):139–145. [PubMed]
Lal C, Strange C, Bachman D. Neurocognitive impairment in obstructive sleep apnea. Chest. 2012;141(6):1601–1610. [PubMed]
Tanno S, Tanigawa T, Maruyama K, Eguchi E, Abe T, Saito I. Sleep-related intermittent hypoxia is associated with decreased psychomotor vigilance in Japanese community residents. Sleep Med. 2017;29:7–12. [PubMed]
Carvalho DZ, St Louis EK, Boeve BF, et al. Excessive daytime sleepiness and fatigue may indicate accelerated brain aging in cognitively normal late middle-aged and older adults. Sleep Med. 2017;32:236–243. [PubMed]
McKay MP. Fatal consequences: obstructive sleep apnea in a train engineer. Ann Fam Med. 2015;13(6):583–586. [PubMed Central][PubMed]
Arita A, Sasanabe R, Hasegawa R, et al. Risk factors for automobile accidents caused by falling asleep while driving in obstructive sleep apnea syndrome. Sleep Breath. 2015;19(4):1229–1234. [PubMed Central][PubMed]
Ward KL, Hillman DR, James A, et al. Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea. J Clin Sleep Med. 2013;9(10):1013–1021. [PubMed Central][PubMed]
Catarino R, Spratley J, Catarino I, Lunet N, Pais-Clemente M. Sleepiness and sleep-disordered breathing in truck drivers : risk analysis of road accidents. Sleep Breath. 2014;18(1):59–68. [PubMed]
Ren R, Li Y, Zhang J, et al. Obstructive sleep apnea with objective daytime sleepiness is associated with hypertension. Hypertension. 2016;68(5):1264–1270. [PubMed]