Current Knowledge/Study Rationale: Obstructive sleep apnea (OSA) and insomnia are very common and both have been independently associated with other serious medical conditions such as cardiovascular disease, cerebrovascular disease, depression, dementia, and cancer. There is some evidence indicating a high prevalence of coexisting insomnia in OSA; however, there are insufficient data on its epidemiology, risk factors, and possibly added risks associated with it.
Study Impact: We have studied the prevalence, associated risk factors, and potential consequences of comorbid insomnia with OSA. There are a fair number of patients with comorbid insomnia and OSA with worsened quality of life and sleep. Comorbid insomnia in OSA is linked to heart disease. Further characterization of this syndrome may help to increase awareness and promote further investigation into its pathogenesis, prevention, and treatment.